An international study has found that urolitsin A,
An international study has found that urolitsin A, a metabolite of natural polyphenols contained in pomegranate fruits and nuts such as walnuts and almonds, helps improve cognitive function in laboratory mice and has the potential to prevent and treat Alzheimer's disease.
Mitochondria are the main sites of cellular respiration. Mitochondrial autophagy can clear damaged or excess mitochondria, and impaired function plays an important role in the occurrence and development of neurodegenerative diseases such as Alzheimer's disease. Researchers from the University of Copenhagen and other research institutions in Denmark recently found through mouse experiments that A natural compound - urolitin A can stimulate mitochondrial autophagy, and long-term treatment with the compound can significantly improve the learning, memory and olfactory functions of mice. Reduce abnormal beta amyloid deposition, Tau protein hyperphosphorylation and other significant pathological features of Alzheimer's disease.
The research team recently published A paper in the journal of Alzheimer's Disease and Dementia in the United States, saying that urolitin A is a natural compound, and natural polyphenol compounds contained in fruits such as pomegranates and some nuts are metabolized by gut microbes to produce urolitin A.
However, the researchers said that it is not certain how much of this substance is needed to improve memory and relieve Alzheimer's symptoms, so it is not recommended to rush to recommend urolixin A dietary supplements to Alzheimer's patients.
Lithuanian media quoted registered dietitian Melissa Prest as saying that the best way to get more urolixin A is to eat foods that stimulate the production of urolixin A in the body, such as pomegranates, nuts, etc. She recommends following a healthy lifestyle at the same time - sleeping at least seven hours a night and getting proper physical activity during the day.