Phosphatidylserine
Phosphatidylserine
Molecular Formula: C42H82NO10P
CAS Number: 51446-62-9
Application: Food industry, Health care and Functional Products; Food additives; Nutritional fortifier;
Description：
Phosphatidylserine is a phospholipid found in the membranes of brain cells and has a protective effect on the cells.Phosphatidylserine plays an important role in keeping the mind and memory sharp as a nutritional supplement. It also helps in relieving stress, sleep and Alzheimer's disease.
Phosphatidylserine (PS) is quite literally a “brain nutrient.” As a matter of fact, this phospholipid is an integral component in the structure of the brain and spinal cord, and is active at cell membranes (including synaptic membrane zones).It plays a key role in cell cycle signaling, specifically in relationship to apoptosis. Studies have provided evidence that PS may promote attention, memory, processing speed, and support overall cognitive health. PS may also support healthy stress and cortisol levels. A significant amount of published clinical research has demonstrated that PS supplementation supports various cognitive parameters in children, including those with ADHD.
Phosphatidylserine is a brain-boosting supplement. It is a class of phospholipids found in cell membranes. Its levels and location within the brain can affect important signaling pathways for cell survival and communication. Phosphatidylserine includes two fatty acids that can vary from saturated or monounsaturated to polyunsaturated omega-6 and omega-3 versions like docosahexaenoic acid (DHA). Some clinical trials of phosphatidylserine supplements have shown modestly improved cognitive function, but better designed trials reported no benefit.
Phosphatidylserine (PS) is a glycerophospholipid consisting of a phosphatidyl group attached to L-serine via a phosphodiester linkage. PS is a critical component of the cellular plasma membrane and accounts for 2-15% of plasma membrane lipid composition, depending on the cell or tissue type. The highest concentrations of PS are found in neuronal tissues, which are critical for maintaining conduction velocity in myelinated neurons, as well as for higher order cognitive skills such as learning and memory. In normal, healthy cells, PS is held in the inner membrane surface (facing the cytosol) by the lipid transporter protein flippase. However, in apoptotic cells, PS molecules ‘shuffle’ between the inner and outer plasma membrane monolayers. When PS molecules flip to the extracellular (outer) surface of the cell membrane, they act as a signal for macrophages to engulf and digest the (apoptotic) cell.
